Sign up now to receive our regular news briefs.

Israeli Researchers Finally Find Good Use For Your Extra Fat

June 13, 2012 11:30 am 0 comments

The Computer Science Faculty building at the Technion Institute for Science in Haifa, Israel. Photo: wiki commons.

According to the UK’s Daily Telegraph, Israeli researchers have made a medical breakthrough in their ability to develop human bone cells through fat cells. Professor Avinoam Kadouri, a leading scientist in industrial biotechnology and head of the scientific advisory board for Bonus BioGroup, predicts that this new discovery will be great news for those suffering with bone fracture injuries and are in need for artificial bones. These new findings may enhance the abilities of physicians and surgeons to replace bones damaged in accidents, fill in cleft palates and other bone defects, and carry out reconstructive plastic surgery.

This development might also improve the latest technologies in human bone repair and could help replace damaged bones with entirely new bones created outside the human body, made from one’s own stem cells. After the most recent round of success, the first trial of stem cell bone-development on human patients will be conducted by an Israeli biotechnology company later this year.

Mesenchymal stem cells were used because they have the capability to develop into many other types of cells in the body. They were obtained from fat using liposuction and then grew into a living bone on the scaffold inside a “bioreactor,” an automated machine that fosters the ideal conditions and environment for mesenchymal stem cells to develop into bone.

The scientists at the Technion Institute for Research waited for nearly a month for these cells to develop into fully-structured live human bone that grew up to two inches in length. They implemented 3D scans of damaged bone to construct a gel-like scaffold formed into the shape of a bone.

“We use three dimensional structures to fabricate the bone in the right shape and geometry,” explained Professor Kadouri about the bone-developing process. “We can grow these bones outside the body and then transplant it to the patient at the right time. By scanning the damaged bone area, the implant should fit perfectly and merge with the surrounding tissue. There are no problems with rejection as the cells come from the patient’s own body.”

Before testing on humans, these artificial bones have been successfully inserted into animals. Scientists at Technion were able to place nearly an inch of a human bone created in the laboratory in the middle section of a rat’s leg bone and fused together with the remainder of the animal’s bone.

Dr. Shai Meretzki, chief executive of Bonus BioGroup, added that they are anticipating this recent development in medical technology to also provide replacements for damaged joints such as hips. “It is the same type of technology, but the equipment would be different for bigger bones,” explained Dr. Meretzki.

Prof. Kadouri also says that the group is in the middle of a project creating the growth of soft cartilage at bone endings, a crucial component for artificial bones being made in laboratories. As of now bone grafts consist of taking pieces of bone from elsewhere in the patient’s body and relocating them to damaged area for the healing process. Using bone from patient’s own body reduces the chances of the new developing bone being rejected than if it had been a bone from an entirely different body.

While research teams from universities and hospitals around the world are developing techniques for growing human bone using stem cells, most have used a different type of stem cells and injected them into the patient rather than growing them into bones outside the body for transplanting them inwards later on.

Leave a Reply

Please note: comments may be published in the Algemeiner print edition. Comments written in all caps will be deleted.


Current day month ye@r *

More...

  • Arts and Culture First English-Language Trailer Debuts for Natalie Portman’s Hebrew Film ‘A Tale of Love and Darkness,’ Based on Amos Oz’s Memoir (VIDEO)

    First English-Language Trailer Debuts for Natalie Portman’s Hebrew Film ‘A Tale of Love and Darkness,’ Based on Amos Oz’s Memoir (VIDEO)

    The first English-language trailer for Natalie Portman’s directorial debut — A Tale of Love and Darkness — based on Israeli author Amos Oz’s memoir, was released on Thursday. The movie, originally filmed in Hebrew, tells the story of Oz’s childhood in Jerusalem at the end of the British Mandate and the early years of Israel’s independence. Portman, who was born in Israel and speaks fluent Hebrew, plays the lead role of Fania, the author’s mother. She struggles to raise her son as she deals with inner demons, a […]

    Read more →
  • Features As Berlin Prices Rise, Israelis Turn East for German Real-Estate Bargains

    As Berlin Prices Rise, Israelis Turn East for German Real-Estate Bargains

    JNS.org – Sonnenallee, a street in Berlin’s Neukölln district, looks like it comes straight out of an Arab city — so much so that it goes by the nickname “Gaza Strip.” Kebab and bakery shops are advertised in Arabic; men sit in men-only coffee shops; and bridal shop windows showcase glittery, not-so-stylish gowns. But take a random turn, and you’ll find a swath of bars, burger joints, and Indian restaurants where hip Berliners announce that they have arrived to urban coolness. […]

    Read more →
  • Arts and Culture Israeli Actress Gal Gadot Slays in ‘Wonder Woman’ Trailer (VIDEO)

    Israeli Actress Gal Gadot Slays in ‘Wonder Woman’ Trailer (VIDEO)

    Israeli actress Gal Gadot engages in fierce action sequences in the new Wonder Woman trailer, which Warner Bros. premiered during the San Diego Comic-Con on Saturday. The nearly 3-minute trailer, the first to debut for the superhero film, shows scenes of Diana, princess of the Amazons, fighting alongside men in the battle against the world’s toughest enemies. The first shot of the video shows Wonder Woman discovering a man, Steve Trevor (played by actor Chris Pine), washed ashore. The clip then takes viewers to the all-female island where Wonder Woman was born. […]

    Read more →
  • Arts and Culture A Theatrical Look at Diplomacy and the Oslo Accords (REVIEW)

    A Theatrical Look at Diplomacy and the Oslo Accords (REVIEW)

    Is diplomacy worthwhile, even if the end result isn’t what we hoped for? That is the question, among many others, posed by the new play Oslo, by J.T. Rogers. Making its New York debut at Lincoln Center, the play examines the secret diplomatic process that led to the historic 1993 peace accords. The character of Shimon Peres makes an appearance onstage — and he, along with Yitzhak Rabin and Yasser Arafat, tower over the proceedings. But they mainly do so in absentia. Instead, […]

    Read more →
  • Spirituality/Tradition Sports Israeli Trailblazer Dean Kremer Brings Jewish Values to Nascent Pro Baseball Career

    Israeli Trailblazer Dean Kremer Brings Jewish Values to Nascent Pro Baseball Career

    JNS.org – Other than being part of the Los Angeles Dodgers organization, Sandy Koufax and Dean Kremer have something else in common: a respect for Jewish tradition. Koufax — who was recently ranked by ESPN as the best left-handed pitcher in Major League Baseball (MLB) history — decided not to pitch Game 1 of the 1965 World Series because the game fell on Yom Kippur. “I would do the same,” Kremer said in an interview. Last month, the 20-year-old Kremer became […]

    Read more →
  • Arts and Culture Lead Guitarist of British Rock Band Queen Asks Adam Lambert to Sing in Hebrew During Upcoming Israel Concert

    Lead Guitarist of British Rock Band Queen Asks Adam Lambert to Sing in Hebrew During Upcoming Israel Concert

    The famed lead guitarist of British rock band Queen, Brian May, encouraged Jewish singer-songwriter Adam Lambert to perform in Hebrew during their upcoming joint concert in Israel, an entertainment industry advocacy organization reported on Tuesday. During a recent interview with Israeli television personality Assi Azar, May was played a 2005 video of Lambert singing the popular song Shir L’Shalom, (Song for Peace). May was so impressed by Lambert’s singing of the Hebrew track that he told the American singer, “We have to do that. Let’s […]

    Read more →
  • Sports Kenyan Marathoner to Compete for Israel in Rio Olympics

    Kenyan Marathoner to Compete for Israel in Rio Olympics

    JNS.org – Kenyan-born marathoner Lonah Chemtai is expected to compete for Israel at the Olympics Games in Rio De Janeiro, Brazil next month after gaining a last minute approval. “I am very proud [to represent Israel] and I hope to achieve a new personal best time,” Chemtai told Reuters. Chemtai, who grew up a rural village in western Kenya, first came to Israel in 2009 to care of the children of her country’s ambassador to Israel. The 27-year-old runner recently gained […]

    Read more →
  • Arts and Culture Jewish Identity Will Laughs Lead to Love on Show About Orthodox Dating?

    Will Laughs Lead to Love on Show About Orthodox Dating?

    To date or not to date? That is not the question for most Modern Orthodox singles in New York. The question is when will they find their future spouses, and when will their families stop nagging them about having babies? Inspired by the success of the Israeli show “Srugim,” Leah Gottfried, 25, decided she would create and star in her own show, “Soon By You.” “Dating is so serious already,” Gottfried said. “We wanted to take a lighter approach and laugh at the […]

    Read more →