In the U.S, diabetes infects some 25 million people, 8 percent of the population, with 2 million being diagnosed each year and 7 million suffering without knowing they have the disease, according to the U.S. National Institute of Health. Nearly a quarter of the country — 79 million adults — are believed to have “pre-diabetes” because of unhealthy conditions, such as obesity.

About 1.5 million diabetics, 5 percent of diagnosed patients, suffer from Type 1 diabetes, also known as juvenile diabetes, because it is often diagnosed in childhood, and insulin-dependent diabetes, because their bodies require a daily injection of the chemical because the amount of sugar in their blood is too high.

In terms of the impact of diabetes on the healthcare system, NIH said direct medical costs total $116 billion annually, plus another $58 billion from diabetics leaving the workforce because their wounds could not cure.

Dr. Adi Zuloff-Shani is one of the original developers of CureXcell since its early stages. She studied immunology at Bar- Ilan University, Ramat-Gan, Israel and worked as a researcher in the R&D unit at Israel’s National Blood Services and at the wound care center in the Sheba Medical Center, in Ramat-Gan,

The company is led by a veteran pharmaceutical executive who sold Omrix Biopharmaceuticals to Johnson & Johnson for $438 million in 2008 and led J&J’s Ethicon for three years. A chemical engineer from Israel’s Technion, in Haifa, and pharmacology scientist from Hebrew University, in Jerusalem, with an MBA from the University of Manchester, England, his name is appropriate for the wonder drug: Nissim Mashiach, Hebrew for Messiah.

MacroCure’s Nasdaq IPO is being led by underwriters Credit Suisse Group, Jefferies LLC, Oppenheimer & Co., and Nomura Securities International Inc.